The Gupta Program is committed to an evidence-based approach for treating chronic conditions. Over the last 20 years, numerous research studies, including randomized controlled trials, have demonstrated that The Gupta Program is highly effective in treating various chronic conditions.
An international audit, conducted by an independent research firm, demonstrated across 16 different chronic conditions that after 3+ months of using The Gupta Program participants experienced a significant increase in overall health and functioning. (These findings were presented at the 2023 IACFS/ME Conference and are being submitted for publication.)
Independent Survey: Percentage Improvement After 3 Months of Using The Gupta Program
















Timeline of Published Research Studies
JULY 2023
Gupta Program Reduces Long COVID Fatigue
In a 3-month randomized controlled trial among people suffering from Long COVID, The Gupta Program significantly reduced fatigue and increased energy. Additionally, the reduction in fatigue and increase in energy were much larger compared to a control group who received a structurally-equivalent wellness program.
Results After 3 Months of Using The Gupta Program
OCTOBER 2020
Gupta Program Reduces Fibromyalgia Symptoms
In an 8-week randomized controlled trial among Fibromyalgia patients, The Gupta Program significantly reduced symptoms and increased health. These improvements were also much greater among those using The Gupta Program compared to a control group who received a structurally-equivalent wellness program.
Results After 8 Weeks of Using The Gupta Program
APRIL 2012
Gupta Program Increases Health & Energy for ME/CFS & Fibromyalgia Patients
In a 3-month randomized controlled trial among people suffering from ME/CFS or Fibromyalgia, The Gupta Program significantly increased physical health and energy, and reduced pain, symptom distress, and fatigue. These improvements far exceeded those experienced by patients who received standard care for ME/CFS or Fibromyalgia.
Results After 3 Months of Using The Gupta Program
September 2010
Gupta Program Improves Health & Functioning for ME/CFS Patients
In a clinical audit of patients with ME/CFS, virtually all participants reported improvement, with two-thirds making considerable recoveries that reached 80%-100% full functioning.
Results After 12 Months of Using The Gupta Program
May 2002
Foundational Hypothesis for the Gupta Program
After several years of suffering from ME/CFS and researching the illness, Ashok Gupta was able to facilitate his own recovery by developing what is now known as The Gupta Program. Though the program has been continually refined and improved over the last two decades, the hypothesis underlying it has remained largely the same. Most people who use The Gupta Program find the hypothesis very helpful in understanding what is happening in their body and how the program can provide a journey to recovery.
Read Ashok’s published paper on the amygdala and insular theory for chronic conditions >